Recently, environmental issues, particularly related to the increasing use of plastics in almost all industrial applications and, consequently, to the disposal of a huge amount of plastic objects at the end of their useful life, are increasingly encouraged both academic and industrial researchers in the study and development of eco-friendly materials solutions. In light of this consideration, under a national project, funded by the Research Ministry and specifically related to the luggage field, authors focused their attention on the production of new environmentally friendly suitcases. For this purpose, two parallel approaches were considered, respectively based on the use of plastic scraps from the recycling chains and the use of biodegradable resins or coming from renewable resources. In the first case, samples were produced by using recycled polyesters from bottle flakes adequately modified by inclusion of opportune toughening and chain extender agents to meet quantitative specifications of the reference market. About the use of bio-based materials, different commercial grades of poly(lactic acid) and polyhydroxy alkanoates resins have been considered still including organic modifiers to improve mechanical performances of products and natural reinforcement fabrics as cotton, jute and flax. Materials were always modified by extrusion and transformed in pure sheets or woven fabric reinforced laminates by compression molding. Investigations carried out in terms of mechanical properties under static, dynamic and impulsive conditions, highlighted good perspectives of the new materials for the reference applications. Finally, suitcase prototypes, specifically designed in order to further improve mechanical performances of products and based on some selected formulations, were produced by thermoforming and validated by specific tests. Results confirmed a significant competitiveness of new eco-sustainable rigid suitcases with respect to commercially ones.